THE INFLUENCE OF THE ENDOVASCULAR INTERVENTION TIMING ON THE POST-INFARCTION PERIOD 

Lukyanova Marina Vladimirovna, Candidate of medical sciences, associate professor, sub-department of therapeutics, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: mavlu2002@gmail.com
Dushina Elena Vladimirovna, Assistant, sub-department of therapeutics, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: dushina-elena@bk.ru
Barmenkova Yulia Andreevna, Assistant, sub-department of therapeutics, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: yulenka.gsk@gmail.com
Oreshkina Anastasia Aleksandrovna, Student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: anast.oreschckina@yandex.ru 

616.127-005.8 

10.21685/2072-3032-2019-2-4 

Purpose. The aim of the study was to evaluate the impact of the percutaneous coronary intervention (PCI) timing on the post-infarction period in patients after myocardial infarction with ST-segment elevation (STEMI).
Materials and methods. The objects of study were 58 patients with STEMI, aged 50,8 ± 8,5 years. All patients underwent multidirectional diagnosis of the postinfarction period: evaluation of quality of life using the Seattle Angina Questionnaire (SAQ) questionnaire, laboratory diagnosis of chronic heart failure (CHF) using the analysis of brain natriuretic peptide (BNP), Holter ECG monitoring (Holter ECG) for the diagnosis of rhythm disorders and episodes of myocardial ischemia.
Results. The quality of life of patients significantly improved by the 12th week by 17 % (p = 0,0004) and 15,3 % (p = 0.004) in both groups according to the SAQ questionnaire. BNP level analysis confirmed the positive dynamics of recovery in the early revascularization group and amounted to 90,6 pg / ml (p = 0,02) by the 24th week of follow-up. Episodes of myocardial ischemia (42,5 %) and the development of life-threatening arrhythmias (42,5 %) according to the Holter ECG were recorded in the group of late revascularization much more often (p = 0,03 and p = 0,005, respectively).
Conclusion. A reduction in the timing of revascularization in patients with STEMI contributes to a more rapid recovery of contractile myocardium and significantly improves the quality of life of patients in the post-infarction period. 

myocardial infarction, percutaneous coronary intervention, quality of life, Holter ECG monitoring 

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